Case Reports Clinical Chemistry 2025 Exercise 5: Myasthenia Gravis in a Seronegative Patient: A Case Report

Authors

Kwaku Twum, PhD

The University of North Carolina at Chapel Hill

Chapel Hill, North Carolina

Kimberly Burgos Villar, PhD

Memorial Sloan Kettering Cancer Center

New York, New York

Yanchun Lin, PhD

Washington University in St Louis School of Medicine

St. Louis, Missouri

Primary Audience: Pathologists and Clinical Scientists
Secondary Audience: Residents, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants,  Laboratory Directors and Educators

Upon completion of this activity, you will be able to:

• evaluate diagnostic decisions of physicians for patients with high suspicion of Myasthenia Gravis (MG);
• educate lab personnel and physicians on limitations of serology testing for diagnosing MG;
•  interpret the clinical significance of electromyography and nerve conduction studies to diagnose seronegative MG; and
• advise on the different modalities and effectiveness of various treatment options for MG symptoms.